NIH Grant Awarded for Multiple Sclerosis Research

Professors Jennifer McDonough (PI) and Ernie Freeman (PI) (Department of Biological Sciences) together with Professor Roger Gregory (co-PI) (Department of Chemistry and Biochemistry) have been awarded a two-year, $398,682 grant from the National Institutes of Health to support their project “Neuronal Expression of Hemoglobin in Multiple Sclerosis Cortex.”

Hemoglobin is a protein that transports oxygen in the blood, but surprisingly, it is also expressed by neurons and may be involved in neuronal respiration. Recent work by the research group at Kent found that hemoglobin expression is increased in multiple sclerosis brain tissue compared with controls [Broadwater et al, Biochimica et Biophysica Acta, 1812 (2011) 630–641]. The goal of this NIH funded research is to understand the regulation and function of hemoglobin expression in neurons, as well as the distribution and extent of hemoglobin expression in the brain and its significance to the neuropathology of multiple sclerosis.

Dr. Roger Gregory
Hemoglobin expression in multiple sclerosis postmortem brain tissue detected by immunofluorescent staining with antibodies to hemoglobin (red) and neurofilament (green).

POSTED: Saturday, September 29, 2012 04:34 PM

UPDATED: Saturday, December 03, 2022 01:02 AM

Where the Classroom Meets the Field

By day, Will Kalkhoff, Ph.D., is a professor in ��ԭ��'s Department of Sociology and Criminology, teaching courses on criminal justice, researching police officer performance and mentoring students on their path to careers in sociology, law enforcement and public safety.

Beyond the Textbook: When Prison Comes to the Classroom

On a November afternoon in Merrill Hall, six women walk into a ��ԭ�� classroom. They're not guest lecturers with advanced degrees. They're currently incarcerated at the Northeast Reintegration Center (NERC) in downtown Cleveland. And for the next couple hours, they'll share their stories—unfiltered, unflinching and deeply human—with students who are beginning to imagine careers in law, corrections, social work and justice reform.

Flash Focus: Lily Stenroos

Meet Lily Stenroos, a member of the Honors College pursuing an environmental studies degree with minors in sustainability, environmental justice and political science, from Mayfield Village, Ohi0, whose academic path was forged from deep relationships between the natural world and humans.

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